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Extension Education | April 2023

Management Strategies for Minimizing Early Pregnancy Loss

Rick Funston, Nebraska Extension Beef Cattle Reproductive Physiologist

University of NE - Lincoln, UNL Beef



As we approach the breeding season, cows and heifers are faced with a variety of stressors from the metabolic pressure of providing for a calf to changes in environment. Stress during early pregnancy is well documented to cause embryonic death and loss of pregnancy. However, making strategic management decisions during the fragile 2 months after breeding can help minimize those losses. Key areas to review management practices to minimize early pregnancy loss are transportation, temperature while being worked or transported, method of pregnancy diagnosis, and nutrition from calving to breeding.


Transportation Stress

Transporting cows to summer pasture oftentimes coincides with the breeding season. Especially, if cows or heifers are artificially inseminated and need to be near working facilities during that time. It is important to plan transportation, or other stressors, strategically to prevent early pregnancy loss and reducing overall pregnancy rates.


Research conducted at Colorado State University has found that transporting cattle between days 5 and 42 post insemination can result in a 10% reduction in pregnancy. This window of time is crucial for blastocyst formation, maternal recognition of pregnancy, and adhesion to the uterine wall. When cattle are loaded into a trailer and transported to a new place, they may become stressed and release a cascade of hormones that can alter the uterine environment making it less ideal for supporting a pregnancy. Prior to day 5, the embryo is still in the oviduct and protected from changes in the uterine environment. After day 42, the embryo has implanted into the uterine wall and is less susceptible to changes in environment. While transporting on days 5 to 42 pose the greatest risk, waiting to haul cows and heifers until a week or two after day 42 may help prevent late embryonic loss. Ultimately, stress during those critical time points may disturb important early embryonic processes and lead to embryonic mortality and increased pregnancy loss.


Some general guidelines for when to transport pregnant cows and heifers post breeding:


Recommended time to haul:

Days 1 - 4 or after day 60


Risk of pregnancy loss:

Days 5 - 55 or 60


Heat Stress

Another key to minimizing pregnancy loss when transportation is necessary, is to avoid hauling cows on excessively hot days (approximately 90° - 110° and 40% humidity or more). Research conducted at Oklahoma State University found that cows exposed to heat stress 8 – 16 days after breeding, had decreased progesterone concentration, increased prostaglandin concentrations, and reduced embryonic weights. A 2 - 2.5 degree increase in rectal temperature (representative measurement of body temperature) for as little as 9 hours has been found to reduce embryo development. Planning to haul cows on days with more moderate temperatures can help reduce stress on heifers and cows and ultimately prevent early pregnancy loss.


Pregnancy Diagnosis

Implementing a pregnancy diagnosis method is key for making sound managerial decisions regarding open females. However, some pregnancy diagnosis methods carry more risk than others regarding early pregnancy loss. Currently, there are 3 options available for pregnancy diagnosis: transrectal palpation, transrectal ultrasound, and a blood test. Obviously, a blood test is the least invasive method but results are not immediate and that may not be practical for producers wanting to sort females on pregnancy check day. Transrectal palpation and transrectal ultrasound allow for immediate results but pose a greater risk for early pregnancy loss and can vary greatly based on stage of pregnancy and skill of the technician. Additional research conducted at Colorado State University found that transrectal palpation between days 42 - 74 had greater fetal losses (2.68 vs 1.38%) than transrectal ultrasound, and that heifers evaluated by inexperienced technicians had greater fetal losses than those evaluated by experienced technicians (2.07 vs 1.06%). It was also found that heifers evaluated prior to 53 days had nearly a 3 fold increase in pregnancy loss than those evaluated after 53 days of pregnancy (3.46 vs 1.26%). While an experienced technician can determine pregnancy by transrectal ultrasound as early as 25 – 30 days or by transrectal palpation by 35 – 45 days, pregnancy diagnosis prior to 40-50 days of pregnancy carries an increased risk of disturbing those fragile early stages of development.


Nutrition at Breeding

It is well established that deficiencies in protein and energy at breeding time has detrimental effects on fertility. Traditionally, it is recommended that cows should be at a BCS of 5 and 1st calf heifers should be at a BCS of 6 at calving for optimal reproductive performance. Managing cows and heifers to be on a positive plane of nutrition at the time of breeding is essential for the establishment of pregnancy. Studies at University of Nebraska have found that thin cows, that are on an increasing plane of nutrition and gaining weight, can have equivalent pregnancy rates as cows in moderate condition that are maintaining their body weight at breeding. However, thin cows that are determined to be losing condition can have a reduction in pregnancy rates up to 30% which may be a result of embryonic loss or anestrous at the time of breeding. Having a sound nutritional program is key to optimizing reproductive function during the breeding season.


Courtesy University of Nebraska - Lincoln, UNL Beef.


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